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BENEFITS Patient benefits over time may include: – Reverses diet-induced obesity – Prevents lipogenesis (fat accumulation) – Treats related metabolic conditions – Increases cellular energy regulators – Increase NAD+ and SAM concentrations in fat cells – Regulates energy expenditure in fat cells SIDE EFFECTS • Headache • Flushing • Nausea SIRT1 is also known as ‘the longevity gene’ because of its role in reducing the risk of diabetes, obesity, metabolic syndrome, atherosclerosis and other forms of cardiovascular disease, kidney disease, liver disease, neurodegeneration, and cancer