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Within cells, scavenging of O 2 • − by small molecules is negligible compared with the rate of removal by endogenous SODs, which have rate constants (~2 × 10 9 M −1 s −1 ) that are millions of times higher than those of most other reactions with O 2 • −

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Since the majority of type 2 diabetes mellitus patients are overweight or obese, a novel term—diabesity—has emerged