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This disease is spread by the pollen of infected plants, as well as by nematodes

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In two 2026 studies, researchers described reishi as a “bioactive-rich, safe, and stable natural ingredient with strong potential for incorporation into cosmetic formulations,”60 and shiitake as a “safe and naturally derived bioactive ingredient … demonstrating promising potential for incorporation into anti-aging and nutraceutical skin-care formulations.”61 There’s the GHK-Cu, too, of course