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Genetic factors, including melanocortin-1 receptor (MC1R), solute carrier family 24 member 5 (SLC24A5), tyrosinase (TYR), and oculocutaneous albinism II (OCA2), significantly impact pigmentation [11]
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An assay based on the blockade of ovulation in cycling rats was used for testing antagonists 19 , and analogs such as [d-Phe2, d-Ala6]-LH-RH and [d-Phe2, d-Leu6]-LH-RH were able to block ovulation and the preovulatory surge of gonadotropin 19
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