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The PRP group had significantly better pain scores at 3 months and 6 months follow-up
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First, Pb 2+ disrupts mitochondrial function, mainly due to Ca overload, including impairing key TCA cycle enzymes such as isocitrate dehydrogenase and α-ketoglutarate dehydrogenase, thereby reducing α-ketoglutarate availability for glutamate synthesis and energy production [109]
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